Involvement of gap junctions in propylthiouracil‑induced cytotoxicity in BRL‑3A cells
نویسندگان
چکیده
منابع مشابه
Gap Junctions Involvement in Brain Hyperexcitability Phenomena
Hyperexcitability pathologies, epitomized by epilepsy, are a largely unmet medical need, asking for conceptual developments on the functioning of networks of inter-communicating neurons and glia. Intercellular communication via gap junction (GJ) channels is largely present in mammalian brain. The GJ channels are made of proteins, essentially the connexins (Cxs) widely expressed in brain and in ...
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Since the initial description of Z immermann (24, 25) who introduced the concept of mesangium, many authors have described characteristic features of the third cell of the mammal ian glomerulus (2 5, 7, 9, 11-13, 18, 20-23). Situated between the basement membrane and the endothelial cells, mesangial cells are stellate cells embedded in the intercellular matrix. They send cytoplasmic projections...
متن کاملGap junctions in development.
Almost since their discovery gap junctions have attracted attention as possible means by which cell growth and cell development could be controlled since they provide for direct cell-cell communication (Potter et al, 1966; Loewenstein, 1968; Sheridan, 1968; Crick, 1970; Bennett, 1973). A corollary, of course, is that gap junctions play an important role in embryogenesis. This idea is made espec...
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Functional Properties of Dendritic Gap Junctions in Cerebellar Golgi Cells
The strength and variability of electrical synaptic connections between GABAergic interneurons are key determinants of spike synchrony within neuronal networks. However, little is known about how electrical coupling strength is determined due to the inaccessibility of gap junctions on the dendritic tree. We investigated the properties of gap junctions in cerebellar interneurons by combining pai...
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ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2019
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2019.7244